The APPLE Tree programme: Active Prevention in People at risk of dementia through Lifestyle, bEhaviour change and Technology to build REsiliEnce

PROJECT STATUS: Ongoing - ending December 2024

The APPLE-Tree study is a randomised controlled trial investigating the clinical (in terms of reducing cognitive decline) and cost effectiveness of the APPLE-Tree programme, a lifestyle and behaviour change group intervention, in individuals at high risk of dementia with mild cognitive impairment or subjective cognitive decline at 24-month follow-up. We are also conducting a process evaluation to explore how the intervention was implemented and explore what factors may determine decisions of NHS and third sector organisations not taking part in the trial, regarding whether they decide to adopt the new intervention, if it is demonstrated to be clinically effective and cost-effective.

There are three PhD students working on the APPLE Tree programme:

  • Christine Carter (UCL): “Understanding how cognitive impairment reconfigures active ageing policies and practices”
  • Brendan Hallam (UCL): “Understanding the incidence, risk factor profile, and risk of dementia in people presenting with memory concerns and cognitive decline in UK primary care”
  • Yolanda Lau (UCL): “Can digital biomarkers be used to identify people with dementia risk?”
Partners & Collaborators

University of East Anglia
University of Exeter
North East London NHS Foundation Trust
University of New South Wales
University of California Davis
Queen Mary University of London

Lead Investigator
Prof Claudia Cooper (UCL)
Dr Michaela Poppe (Programme Manager, QMUL)
Investigating Team
Christine Carter, (PhD, UCL)
Brendan Hallam (PhD, UCL)
Yolanda Lau (PhD, UCL)
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